Searchable abstracts of presentations at key conferences in endocrinology

ea0056p505 | Diabetes therapy | ECE2018

A latent autoimmune diabetes in adults (LADA) case renamed after six years of diabetes diagnosis when complicated with diabetic ketoacidosis induced by dapagliflozin

Ekiz-Bilir Betul , Bilir Bulent , Elbuken Gulsah

Introduction: LADA (Latent autoimmune diabetes in adults) is an adult-onset and more indolent variety of autoimmune type 1 diabetes mellitus. In autoimmune diabetes, younger individuals typically have a rapid rate of beta-cell destruction and usually present with ketoacidosis, while adults often maintain sufficient insulin secretion to prevent ketoacidosis for many years. LADA is usually misdiagnosed initially as type 2 diabetes due to its late onset but LADA patients are anti...

ea0049ep446 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

The relationship between serum uric acid and insulin resistance and sensitivity parameters in Turkish type 2 diabetes mellitus patients

Ekiz-Bilir Betul , Bilir Bulent , Soysal-Atile Neslihan , Elbuken Gulsah

Summary: Hyperuricemia is associated with glucose metabolism disorders clinically. In this study, we evaluated the relationship between serum uric acid concentrations and some insulin resistance/sensitivity parameters in Turkish type 2 diabetes mellitus patients.Methods: The anthropometric and laboratory data of 87 type 2 diabetes patients of both sexes (35 male, 52 female) were evaluated retrospectively. HOMA-IR (homeostatic model of insulin resistance)...

ea0041ep214 | Cardiovascular Endocrinology and Lipid Metabolism | ECE2016

Impact of overweight and obesity on cardiac diastolic function

Soysal Atile Neslihan , Baykiz Derya , Ekiz Bilir Betul , Bilir Bulent

Introduction: Left ventricular diastolic dysfunction (LVDD) is a common cause of heart failure in obese patients. The aim of this study is to evaluate diastolic function and its relation to body mass index (BMI) in overweight and obese patients by using transthoracic echocardiography.Material and method: A total of 133 cases were enrolled in the study. All anthropometric and laboratory measures were recorded. After measuring two-dimensional and M-mode ec...

ea0037ep1304 | Clinical Cases–Thyroid/Other | ECE2015

Coexistent medullary and papillary thyroid carcinomas

Ekiz-Bilir Betul , Soysal-Atile Neslihan , Dagli Zehra , Coskunkan Ufuk

Papillary thyroid cancer (PTC) is the most frequent thyroid tumour. Medullary thyroid cancer (MTC) however, is very rare. We report a case of coexistent medullary and papillary carcinomas in two different foci in a patient with family history of TPC in a first-degree relative.Case: A 65-year-old female was examined for multinodular goiter (MNG). She had a family history of thyroid papillary carcinoma in her elder sister. Free T4, free T3<...

ea0026p516 | Bone/calcium/Vitamin D | ECE2011

Hungry bone syndrome following parathyroidectomy

Soysal Atile Neslihan , Ekiz Bilir Betul , Guldiken Sibel

Aim: Hypocalcemia is a common problem after parathyroidectomy but is generally transient. In some cases the postoperative hypocalcemia is severe and prolonged despite normal or even elevated levels of parathyroid hormone (PTH). This phenomenon, called the hungry bone syndrome (HBS), occurs due to sudden withdrawal of PTH leading to a marked net increase in bone uptake of Ca, P, and Mg. We aimed to evaluate predictive factors for HBS development after parathyroidectomy.<p c...

ea0049ep842 | Clinical case reports - Pituitary/Adrenal | ECE2017

A hypopituitarism case diagnosed after sphenoid sinus mucocele operation

Ekiz-Bilir Betul , Bilir Bulent , Oz Aysel , Gunes-Ciftci Halide , Soysal-Atile Neslihan , Elbuken Gulsah

Introduction: Mucoceles-mucus containing benign cysts of paranasal sinuses- are common with an incidence of 1% but involvement of sphenoid sinus is much less common. In this case report, we reported a patient presented with hypopituitarism after sphenoid mucocele drainage operation.Case report: A 59- year-old woman was admitted to our endocrinology out-patient clinics with a complaint of fatigue over the past 2 months. One month prior to admission, she h...

ea0041ep1060 | Thyroid (non-cancer) | ECE2016

Thyrolipoma: a rare entity of the thyroid gland

Ekiz Bilir Betul , Ozturk Ozlem , Bilir Bulent , Soysal Atile Neslihan , Ozkan Hakan

Introduction: Thyrolipoma (focal adenolipoma of thyroid gland) and thyrolipomatosis (diffuse lipomatosis in the gland) are rarely encountered pathologies in daily practice. We reported a case of small thyrolipoma incidentally diagnosed in a multinodular goiter patient.Case report: A 56 year-old man was admitted to our out-patient clinics with the complaint of a lump in his cervical region. His thyroid function tests were normal. In physical examination, ...

ea0037ep582 | Obesity and cardiovascular endocrinology | ECE2015

Neutrophil to lymphocyte ratio as an inflammatory marker in obesity

Soysal-Atile Neslihan , Ekiz-Bilir Betul , Bilir Bulent , Baykiz Derya , Topcu Birol , Aydin Murat

Aim: Cardiovascular morbidity and mortality of obesity is associated with classic risk factors, namely dyslipidaemia, hypertension and impaired glucose metabolism. Aim of this study is to evaluate inflammation as an independent risk factor by using neutrophil to lymphocyte ratio (NLR).Materials and methods: Patients who admitted to our outpatient clinic between January and December 2014 were assessed retrospectively. Patients diagnosed as diabetes, predi...

ea0037ep623 | Obesity and cardiovascular endocrinology | ECE2015

Relationship between TSH and cortisol levels in euthyroid obese subjects

Soysal-Atile Neslihan , Ekiz-Bilir Betul , Bilir Bulent , Kara Sonat Dilek

Several studies have reported that TSH is positively correlated with obesity, dyslipidaemia, and impaired glucose metabolism even in normal range limits. We aimed to evaluate the TSH levels in a cohort of otherwise healthy obese women without clinical evidence of thyroid dysfunction.Materials and methods: 127 female patients were enrolled in this study. Anthropometric and laboratory measurements were retrospectively analysed. Patients were divided into s...

ea0026p324 | Obesity | ECE2011

Basal energy expenditure and fat mass changes in breast cancer patients

Tuncbilek Nermin , Guldiken Sibel , Soysal Atile Neslihan , Ekiz Bilir Betul , Koken Deniz

Aim: Basal energy expenditure (BEE), also called basal metabolic rate, increases in cancer patients and is thought to contribute to the weight loss observed in cancer cachexia. Cancer type, pathological stage and duration of disease influence BEE. The aim of this study was to evaluate BEE and body composition in breast cancer patients.Methods: Forty-three women with breast cancer whose received adjuvant chemotherapy and 80 healthy age and body mass index...